The Science

Real results start with real science.

At BioFollix, every ingredient in our formula is chosen based on research, not marketing trends.
Our serum targets the root cause of male hair loss: DHT buildup and follicle inflammation. By combining Multi-Peptides, Saw Palmetto, Rosemary, Eucalyptus, and Baicalin, we’ve created a synergistic formula that helps block DHT, improve circulation, and support healthy follicle regeneration.

Because when science meets nature, confidence grows back naturally.

Our clinically backed hair growth formula:

Ingredient listing

Peptides and Growth Factors

  • Ingredients like sh-Polypeptide-1 (IGF-1), sh-Polypeptide-9 (KGF), sh-Oligopeptide-10 (aFGF), and sh-Oligopeptide-2 are synthetic versions of human growth factors and peptides increasingly studied for topical hair growth effects.​
  • These peptides have shown in some clinical settings to stimulate hair follicle activity, extend the growth (anagen) phase, and improve density and thickness.

Key Amino Acids and Nutrients

  • Arginine is a primary building block for hair keratin and can promote scalp blood flow and provide hydration via its film-forming properties.​
  • Tocopherol (Vitamin E) functions as an antioxidant, protecting hair follicles from oxidative stress, which is beneficial for overall hair quality.​
  • Lecithin is an emollient and may aid barrier function.

Plant Extracts (Saw Palmetto, Rosemary, Eucalyptus, Scutellaria)

  • Saw Palmetto Extract can block 5-alpha reductase, lowering DHT, a well-known trigger for pattern hair loss.​
  • Rosemary Extract is documented to enhance scalp circulation, reduce inflammation, and create an ideal environment for hair growth.​
  • Scutellaria Baicalensis Root Extract, along with Soybean and Wheat Germ extracts, forms the Baicapil blend, tested for its ability to boost the anagen/telogen (growth/rest) hair ratio and reduce hair loss (mostly manufacturer-funded studies).​

Glycerin, Citric Acid, Lactic Acid, Xanthan Gum

  • Glycerin provides hydration and supports scalp barrier health, essential for preventing hair breakage and maintaining hair texture, but evidence for directly stimulating hair growth is insufficient.​
  • Citric Acid and Lactic Acid regulate scalp pH and exfoliate, which may indirectly support follicle health but do not directly stimulate growth.​
  • Xanthan Gum is used primarily as a formulation stabilizer.

Safety and Supportive Ingredients

  • Sodium Benzoate, Gluconolactone, Calcium Gluconate, Potassium Sorbate, Propanediol: These are generally used as preservatives or solvents, playing little to no direct role in promoting hair growth.
  • Water: Vehicle and hydrator, not a stimulant for growth.
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Scientific studies

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Sources:

Here is a list of the key ingredients from our list with primary source links relevant to hair growth:

  1. sh-Polypeptide-1 (IGF-1 / IGF-1 in hair regeneration)
    Hsieh WJ, et al. Insulin-like Growth Factor 1 (IGF-1) in Hair Regeneration. MDPI 47, 773 (2025). https://www.mdpi.com/1467-3045/47/9/773 (MDPI)
    (Also see a related survey: Further Clinical Evidence for the Effect of IGF-1 on Hair Loss (PMC) (PMC))
  2. AIMP1-Derived Peptides activating hair follicle / dermal papilla cells
    Kim Y, Lee H, Kim D, et al. AIMP1-Derived Peptide Secreted from Hair Follicle Stem Cells Activates Dermal Papilla Cells to Promote Hair Growth. International Journal of Biological Sciences. 2024;20(14):5764–5778. DOI: 10.7150/ijbs.101127. PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11528461/ (PMC)
  3. Saw Palmetto Extract (5-alpha reductase inhibition)
    Rossi A, Cantisani C, Melis L, Iorio A, Scali E, Calvieri S. Saw Palmetto (Serenoa repens) in Androgenetic Alopecia: A Systematic Review. Dermatologic Therapy. 2011;24(3):177–90. PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC7706486/
  4. Rosemary Extract / Rosemary Oil for hair regrowth
    Panahi Y, Taghizadeh M, Marzony ET, Sahebkar A. Rosemary Oil vs. Minoxidil 2% for the Treatment of Androgenetic Alopecia: A Randomized Comparative Trial. Skinmed. 2015;13(1):15–21. PMID: 28905270 (PubMed) https://pmc.ncbi.nlm.nih.gov/articles/PMC11549889/
  5. Arginine’s role in hair / scalp health (nitric oxide, vascular effects)
    https://pubmed.ncbi.nlm.nih.gov/33878855/
  6. Tocopherol (Vitamin E) antioxidant effects on hair
    (PMC article: Topical Vitamin E and Hair Health, PMC ID: 4960454) — link: https://pmc.ncbi.nlm.nih.gov/articles/PMC3819075/
  7. Baicapil blend (Scutellaria, Soybean, Wheat Germ) — hair growth promotion
    Farkash B, Ginis I, Alpert O, et al. A Novel Complex of Botanical Extracts (Baicapil®): In Vitro and In Vivo Evidence for Hair-Promoting Activity. PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC5810219/
  8. Glycerin (Humectant role in scalp hydration / moisture retention)
    (PMC / PubMed: Humectant role of glycerin in skin / stratum corneum / hydration, PMID 12628859) — link: https://pubmed.ncbi.nlm.nih.gov/18510666/
  9. Citric Acid & Lactic Acid (pH adjustment, gentle exfoliation, skin barrier effects)
    (PMC article: Acids in Skin Barrier Function, PMC ID: 5605218) — link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/
  10. Xing F, Yi WJ, Miao F, Su MY, Lei TC. Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice. Int J Mol Med. 2018 Apr;41(4):2079-2085. doi: 10.3892/ijmm.2018.3391. Epub 2018 Jan 16. PMID: 29336472; PMCID: PMC5810219.
  11. Chen L, Fan B, Gu H, Yang L, Li X. Effects of Baicalin on Alopecia and the Associated Mechanism. Biomed Res Int. 2022 Nov 18;2022:3139123. doi: 10.1155/2022/3139123. PMID: 36440360; PMCID: PMC9699788.
  12. Wang S, Meng D, Wang S, Zhang Z, Yang R, Zhao W. Modification of wheat gluten for improvement of binding capacity with keratin in hair. R Soc Open Sci. 2018 Feb 7;5(2):171216. doi: 10.1098/rsos.171216. PMID: 29515840; PMCID: PMC5830729.
  13. Burnett C, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA, Heldreth B. Safety Assessment of Hydrolyzed Wheat Protein and Hydrolyzed Wheat Gluten as Used in Cosmetics. Int J Toxicol. 2018 May/Jun;37(1_suppl):55S-66S. doi: 10.1177/1091581818776013. PMID: 29761728.
  14. Rossi, A., Mari, E., Scarno, M., Garelli, V., Maxia, C., Scarnò, M., Fortuna, M. C., & Carlesimo, M. (2012). Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: A two-year study. International Journal of Immunopathology and Pharmacology, 25(4), 1167–1173. https://doi.org/10.1177/039463201202500428
  15. Wessagowit, V., Tangjaturonrusamee, C., Kootiratrakarn, T., Bunnag, T., Pimonrat, T., Muangdang, N., & Asawanonda, P. (2016). Treatment of male androgenetic alopecia with topical products containing Serenoa repens extract. Australasian Journal of Dermatology, 57(3), e76–e82. https://doi.org/10.1111/ajd.12358
  16. Murata, K., Noguchi, K., Kondo, M., Onishi, M., Watanabe, N., Okamura, K., Matsuda, H., & Takahashi, T. (2018). Promotion of hair growth by topical application of peptides. International Journal of Molecular Sciences, 19(9), 2706. https://doi.org/10.3390/ijms19092706
  17. Dhurat, R., Sukesh, M., Avhad, G., Dandale, A., & Pal, A. (2013). A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia. International Journal of Trichology, 5(1), 6–11. https://doi.org/10.4103/0974-7753.114700
  18. Suchonwanit, P., Thammarucha, S., & Leerunyakul, K. (2019). Minoxidil and its use in hair disorders: A review. Drug Design, Development and Therapy, 13, 2777–2786. https://doi.org/10.2147/DDDT.S214907
  19. Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P., & Tosti, A. (2019). The role of vitamins and minerals in hair loss: A review. Dermatology and Therapy, 9(1), 51–70. https://doi.org/10.1007/s13555-018-0278-6
  20. Ho, C. H., Sood, T., & Zito, P. M. (2023). Androgenetic alopecia. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430924/
  21. Trueb, R. M. (2002). Oxidative stress in ageing of hair. International Journal of Trichology, 4(3), 116–118.
  22. Rinaldi, F., Trink, A., Pinto, D., Giuliani, G., & Peretta, G. (2015). Human hair growth enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG). Phytomedicine, 22(5), 490–495.