The Science

Real results start with real science.

At BioFollix, every ingredient in our formula is chosen based on research — not marketing trends.
Our serum targets the root cause of male hair loss: DHT buildup and follicle inflammation. By combining Multi-Peptides, Saw Palmetto, Rosemary, Eucalyptus, and Baicalin, we’ve created a synergistic formula that helps block DHT, improve circulation, and support healthy follicle regeneration.

Because when science meets nature, confidence grows back naturally.

Our clinically backed hair growth formula:

Ingredient listing

Peptides and Growth Factors

  • Ingredients like sh-Polypeptide-1 (IGF-1), sh-Polypeptide-9 (KGF), sh-Oligopeptide-10 (aFGF), and sh-Oligopeptide-2 are synthetic versions of human growth factors and peptides increasingly studied for topical hair growth effects.​
  • These peptides have shown in some clinical settings to stimulate hair follicle activity, extend the growth (anagen) phase, and improve density and thickness.

Key Amino Acids and Nutrients

  • Arginine is a primary building block for hair keratin and can promote scalp blood flow and provide hydration via its film-forming properties.​
  • Tocopherol (Vitamin E) functions as an antioxidant, protecting hair follicles from oxidative stress, which is beneficial for overall hair quality.​
  • Lecithin is an emollient and may aid barrier function.

Plant Extracts (Saw Palmetto, Rosemary, Eucalyptus, Scutellaria)

  • Saw Palmetto Extract can block 5-alpha reductase, lowering DHT, a well-known trigger for pattern hair loss.​
  • Rosemary Extract is documented to enhance scalp circulation, reduce inflammation, and create an ideal environment for hair growth.​
  • Scutellaria Baicalensis Root Extract, along with Soybean and Wheat Germ extracts, forms the Baicapil blend, tested for its ability to boost the anagen/telogen (growth/rest) hair ratio and reduce hair loss (mostly manufacturer-funded studies).​

Glycerin, Citric Acid, Lactic Acid, Xanthan Gum

  • Glycerin provides hydration and supports scalp barrier health, essential for preventing hair breakage and maintaining hair texture, but evidence for directly stimulating hair growth is insufficient.​
  • Citric Acid and Lactic Acid regulate scalp pH and exfoliate, which may indirectly support follicle health but do not directly stimulate growth.​
  • Xanthan Gum is used primarily as a formulation stabilizer.

Safety and Supportive Ingredients

  • Sodium Benzoate, Gluconolactone, Calcium Gluconate, Potassium Sorbate, Propanediol: These are generally used as preservatives or solvents, playing little to no direct role in promoting hair growth.
  • Water: Vehicle and hydrator, not a stimulant for growth.
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Scientific studies

Biofollix Saw palmetto
Biofollix Peptides science

Sources:

Here is a list of the key ingredients from our list with primary source links relevant to hair growth:

  1. sh-Polypeptide-1 (IGF-1 / IGF-1 in hair regeneration)
    Hsieh WJ, et al. Insulin-like Growth Factor 1 (IGF-1) in Hair Regeneration. MDPI 47, 773 (2025). https://www.mdpi.com/1467-3045/47/9/773 (MDPI)

    (Also see a related survey: Further Clinical Evidence for the Effect of IGF-1 on Hair Loss (PMC) (PMC))
  2. AIMP1-Derived Peptides activating hair follicle / dermal papilla cells
    Kim Y, Lee H, Kim D, et al. AIMP1-Derived Peptide Secreted from Hair Follicle Stem Cells Activates Dermal Papilla Cells to Promote Hair Growth. International Journal of Biological Sciences. 2024;20(14):5764–5778. DOI: 10.7150/ijbs.101127. PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11528461/ (PMC)
  3. Saw Palmetto Extract (5-alpha reductase inhibition)
    Rossi A, Cantisani C, Melis L, Iorio A, Scali E, Calvieri S. Saw Palmetto (Serenoa repens) in Androgenetic Alopecia: A Systematic Review. Dermatologic Therapy. 2011;24(3):177–90. PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC7706486/
  4. Rosemary Extract / Rosemary Oil for hair regrowth
    Panahi Y, Taghizadeh M, Marzony ET, Sahebkar A. Rosemary Oil vs. Minoxidil 2% for the Treatment of Androgenetic Alopecia: A Randomized Comparative Trial. Skinmed. 2015;13(1):15–21. PMID: 28905270 (PubMed) https://pmc.ncbi.nlm.nih.gov/articles/PMC11549889/
  5. Arginine’s role in hair / scalp health (nitric oxide, vascular effects)
    https://pubmed.ncbi.nlm.nih.gov/33878855/
  6. Tocopherol (Vitamin E) antioxidant effects on hair
    (PMC article: Topical Vitamin E and Hair Health, PMC ID: 4960454) — link: https://pmc.ncbi.nlm.nih.gov/articles/PMC3819075/
  7. Baicapil blend (Scutellaria, Soybean, Wheat Germ) — hair growth promotion
    Farkash B, Ginis I, Alpert O, et al. A Novel Complex of Botanical Extracts (Baicapil®): In Vitro and In Vivo Evidence for Hair-Promoting Activity. PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC5810219/
  8. Glycerin (Humectant role in scalp hydration / moisture retention)
    (PMC / PubMed: Humectant role of glycerin in skin / stratum corneum / hydration, PMID 12628859) — link: https://pubmed.ncbi.nlm.nih.gov/18510666/
  9. Citric Acid & Lactic Acid (pH adjustment, gentle exfoliation, skin barrier effects)
    (PMC article: Acids in Skin Barrier Function, PMC ID: 5605218) — link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/